The Orange Pill Podcast
The Orange Pill Podcast 🎙️ Your go-to source for the latest in the dietary supplement and natural health product industry! Brought to you by KGK Science, a global leader in clinical research and regulatory consulting, this podcast delivers: ✔️ Breaking industry news and trends ✔️ Educational insights and practical takeaways ✔️ Discussions on cutting-edge research ✔️ Landmark cases and notable events shaping the field Join us as we bridge the gap between science, regulation, and everyday impact.
Episodes

Tuesday May 13, 2025
Episode 22: Pollen Extracts for Female Urinary incontinence
Tuesday May 13, 2025
Tuesday May 13, 2025
In this episode, we explore how flower pollen extracts are being studied as a potential solution for urinary incontinence in women. We break down the latest clinical evidence from a newly published trial in Current Urology, conducted by KGK Science and sponsored by Graminex®.
We’ll discuss:
The impact of urinary incontinence on daily life
How flower pollen extracts may support urinary health
Key findings from the clinical trial
What this means for the future of women’s health and nutraceuticals
Don't miss this deep dive into one of the most under-discussed yet important areas of women's health.

Thursday May 08, 2025
Episode 21: The Sleep Secret Hidden in Corn Leaves
Thursday May 08, 2025
Thursday May 08, 2025
We are back with a deep dive into the world of sleep — and why melatonin may not be the long-term solution we’ve all been promised.
In this episode we cover:
Why melatonin is widely used in hospitals, yet many still struggle to sleep
What makes sleep so critical to overall health
The growing global demand for new, effective sleep supplements
A look at Maizinol®, a natural sleep aid derived from corn leaves, clinically shown to improve REM sleep, reduce sleep latency, and extend overall sleep time — all from a single dose. The science is in, and the results are impressive.

Tuesday May 06, 2025
Episode 20: History of the US Food Supply : Before and After FDA
Tuesday May 06, 2025
Tuesday May 06, 2025
In this episode, we uncover the shocking state of America’s food supply before the FDA — from toxic milk to candy laced with arsenic — and explore how those chaotic beginnings shaped the future of food, supplements, and regulation.

Thursday May 01, 2025
Episode 19: KGK Science and Nimble Science: Revolutionizing GI Health Research
Thursday May 01, 2025
Thursday May 01, 2025
In this episode of the Orange Pill Podcast, we talk about the exciting new partnership between KGK Science and Nimble Science. Learn how this collaboration is set to redefine gastrointestinal (GI) health research through the integration of SIMBA™, a novel ingestible capsule that collects high-quality gut samples—without invasive procedures.

Tuesday Apr 29, 2025
Episode 18: RFK Jr.'s FDA Food Safety Agenda
Tuesday Apr 29, 2025
Tuesday Apr 29, 2025
In this episode, we dive into U.S. presidential candidate Robert F. Kennedy Jr.’s provocative vision for the future of food regulation. RFK Jr. is calling for nothing short of a revolution—taking aim at food chemicals, plastics, and the FDA’s current approach to food safety.
We unpack his stance on rethinking Generally Recognized as Safe (GRAS) determinations, his plan to reform the FDA’s oversight of food additives and endocrine disruptors, and what this could mean for food manufacturers, consumers, and the natural health industry.

Thursday Apr 24, 2025
Episode 17: Yeast Postbiotic Effect On Cold And Flu In Children
Thursday Apr 24, 2025
Thursday Apr 24, 2025
In this episode, we unpack a compelling clinical study conducted by KGK Science for Cargill on the impact of EpiCor® postbiotic supplementation in children. Learn how a daily gummy dose of this yeast-derived ingredient significantly reduced cold and flu symptoms, limited the need for medication, and offered a safe, science-backed immune support option for kids aged 4 to 12. Plus, we explore why this study is a milestone in both postbiotic and gummy supplement research.

Tuesday Apr 22, 2025
Tuesday Apr 22, 2025
In this episode, we dive into a recent Lancet meta-analysis that questions vitamin D’s effectiveness in preventing acute respiratory infections. What does the data actually say, and how should consumers respond?
We also explore promising new findings from Pediatric Research on EpiCor, a postbiotic that may reduce cold and flu symptom severity in children. KGK Science contributed to this important study—hear what the results mean for immune health innovation and the supplement industry at large.

Thursday Apr 17, 2025
Episode 15: Upcoming Trends in 2025 for the Dietary Supplement Industry
Thursday Apr 17, 2025
Thursday Apr 17, 2025
In this forward-looking episode, we explore the major shifts on the horizon for the dietary supplement and nutraceuticals sector in 2025. Expect a transformation driven by sustainability, science, and personalization. We cover:
The rise of plant-based and functional ingredients
Personalized nutrition through genomics and AI
Regulatory updates on GRAS and novel ingredients
The role of eco-conscious practices and clean-label demands
Digital health tech and real-time supplement customization
Insights into cutting-edge clinical research, like KGK’s study on immune health in children
If you're in the industry—or just passionate about where wellness is headed—this is an episode you don't want to miss.

Tuesday Apr 15, 2025
Episode 14: Disturbing New Trend in CRO Research- Use of Predicted Margins
Tuesday Apr 15, 2025
Tuesday Apr 15, 2025
In this episode, we explore a growing issue in nutraceutical clinical research: the misuse of predicted margins to gloss over incomplete data in virtual trials. When predictive models are used in place of raw results—without validation or transparency—scientific rigor is compromised. We break down what predicted margins are, when they should (and shouldn’t) be used, and how this impacts regulatory credibility.

Thursday Apr 10, 2025
Episode 13: FDA's Final Rule for 'Healthy'
Thursday Apr 10, 2025
Thursday Apr 10, 2025
In this episode, we explore the FDA’s newly finalized definition of “healthy” for food labeling — a major regulatory update released in December 2024. The goal? To bring food labels in line with today’s nutrition science and help consumers make better choices.
We unpack what’s changed, why it matters, and how these new rules will impact how companies across both the supplement and conventional food spaces position their products moving forward.